A 72 y/o 50kg female presents to the ER complaining of blurred vision, nausea and vomiting. A physical exam found right unilateral weakness and numbness. During the exam, she experienced a seizure and became comatose. Bloodwork found:
Serum [Na+] 140 mEq/L
Serum [K+] 4.2 mEq/L
Serum [HCO3-] 27 mEq/L
PCO2 41 mmHg
Serum creatinine 1.0 mg/dl
The physician immediately ordered an infusion of 5 g/kg mannitol. After equilibration, how would the body volumes change if one assumes that no excretion occurs and that the volume of the mannitol solution is 1000 ml. (3pts)
How would this benefit the patient acutely (1pt)? Chronically (1pt)?
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